On 15 January 2019, May's government was defeated in the House of Commons by a margin of 230 votes (202 in favour and 432 opposed) in a vote on her deal to leave the European Union. It was the largest majority against a United Kingdom government in history.
On 7 March 2019, the Queen hosted a Buckingham Palace event to mark the 50th anniversary of Charles's investiture as the Prince of Wales. Guests at the event included the Duchess of Cornwall, the Duke and Duchess of Cambridge, the Duke and Duchess of Sussex, Prime Minister Theresa May and Welsh First Minister Mark Drakeford.
On 18 March 2019, the Speaker (Speaker of the House of Commons) informed the House of Commons that a third meaningful vote could be held only on a motion that was significantly different from the previous one, citing parliamentary precedents going back to 1604.
After the government deemed unwarranted the concerns over the legality of the proposed change (because it contained two possible exit dates) the previous day, on 27 March 2019 both the Lords (without a vote) and the Commons (by 441 to 105) approved the statutory instrument changing the exit date to 22 May 2019 if a withdrawal deal is approved, or 12 April 2019 if it is not. The amendment was then signed into law at 12:40 p.m. the next day.
The first alternative offered was that if MPs rejected May's deal in the next week, Brexit would be due to occur by 12 April 2019, with, or without, a deal—or alternatively another extension be asked for and a commitment to participate in the 2019 European Parliament elections given.
Barcelona suffered a 4–0 away defeat, which saw Liverpool advance to the final 4–3 on aggregate, leaving the UEFA Champions League. Six days before, Messi scored twice in a 3–0 home win over Liverpool in the first leg of the Champions League semi-finals; his second goal of the match, a 35-yard free-kick, was the 600th senior club goal of his career, all of which had been scored with Barcelona.
On 22 May 2019, Arm Holdings also suspended its business with Huawei, including all "active contracts, support entitlements, and any pending engagements". Although it is a Japanese-owned company based in the UK, Arm cited that its intellectual property contained technologies of U.S. origin that it believed were covered under the Department of Commerce order. This prevents Huawei from manufacturing chips under the ARM architecture.
The UK Parliament passed the European Union (Withdrawal) (No. 2) Act 2019, which received Royal Assent on 9 September 2019, obliging the Prime Minister to seek a third extension if no agreement has been reached at the next European Council meeting in October 2019.
Subsequently, the government introduced a bill to ratify the withdrawal agreement. It passed its second reading in the House of Commons in a 358–234 vote on 20 December, and became law on 23 January as the European Union (Withdrawal Agreement) Act 2020.