Seleucid Empire - Seleucus II was soon dramatically defeated in the Third Syrian War
Time: 240s BC
Place: Syria
Details: Seleucus II was soon dramatically defeated in the Third Syrian War against Ptolemy III of Egypt and then had to fight a civil war against his own brother Antiochus Hierax. Taking advantage of this distraction, Bactria and Parthia seceded from the empire.
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