What happened 1505 AD

Circa 1505, Raphael executed a pen-and-ink sketch, in which the columns flanking the subject are more apparent. Experts universally agree that it is based on Leonardo's portrait. Other later copies of the Mona Lisa, such as those in the National Museum of Art, Architecture and Design and The Walters Art Museum, also display large flanking columns. As a result, it was thought that the Mona Lisa had been trimmed.

Leonardo then spent two years in Florence designing and painting a mural of The Battle of Anghiari for the Signoria, with Michelangelo designing its companion piece, The Battle of Cascina.

In the 16th century Sixtus V bisected Bramante's Cortile del Belvedere with a cross-wing to house the Apostolic Library in suitable magnificence.