The Mona Lisa began influencing contemporary Florentine painting even before its completion. Raphael, who had been to Leonardo's workshop several times, promptly used elements of the portrait's composition and format in several of his works, such as Young Woman with Unicorn (c. 1506), and Portrait of Maddalena Doni (c. 1506). Later paintings by Raphael, such as La velata (1515–16) and Portrait of Baldassare Castiglione (c. 1514–15), continued to borrow from Leonardo's painting.
In 1506, Leonardo was summoned to Milan by Charles II d'Amboise, the acting French governor of the city. The Council of Florence wished Leonardo to return promptly to finish The Battle of Anghiari, but he was given leave at the behest of Louis XII, who considered commissioning the artist to make some portraits.
The castle and surrounding land remained with the Bubenberg family until their extinction in 1506, when it was acquired by Ludwig von Diesbach. Von Diesbach held it for ten years before Ludwig von Erlach acquired the castle and lands.
Amenhotep I probably left no male heir and the next pharaoh, Thutmose I, seems to have been related to the royal family through marriage. During his reign the borders of Egypt's empire reached their greatest expanse, extending in the north to Carchemish on the Euphrates and in the south up to Kurgus beyond the fourth cataract of the Nile.