In 1526 Spanish Conquistador Francisco de Montejo successfully petitioned the King of Spain for a charter to conquer Yucatán. His first campaign in 1527, which covered much of the Yucatán Peninsula, decimated his forces but ended with the establishment of a small fort at Xaman Haʼ, south of what is today Cancún.
The empire's push into the Amazon Basin near the Chinchipe River was stopped by the Shuar in 1527. The empire extended into the corners of Argentina and Colombia. However, most of the southern portion of the Inca empire, the portion denominated as Qullasuyu, was located in the Altiplano.