Soon after the Conference began, the US government learned that Luciano was in Cuba. Luciano had been publicly fraternizing with Sinatra as well as visiting numerous nightclubs, so his presence was no secret in Havana. The US started putting pressure on the Cuban government to expel him. On February 21, 1947, U.S. Narcotics Commissioner Harry J. Anslinger notified the Cubans that the US would block all shipment of narcotic prescription drugs while Luciano was there.
Nosek, backed by Gottwald, refused to yield. He and his fellow Communists threatened to use force and, in order to avoid defeat in parliament, mobilised groups of their supporters in the country. On 21 February, twelve non-Communist ministers resigned in protest after Nosek refused to reinstate eight non-Communist senior police officers despite a majority vote of the cabinet in favour of doing so.
On February 21, 1965, he was preparing to address the OAAU in Manhattan's Audubon Ballroom when someone in the 400-person audience yelled, "Nigger! Get your hand outta my pocket!" As Malcolm X and his bodyguards tried to quell the disturbance, a man rushed forward and shot him once in the chest with a sawed-off shotgun and two other men charged the stage firing semi-automatic handguns. Malcolm X was pronounced dead at 3:30 pm, shortly after arriving at Columbia Presbyterian Hospital. The autopsy identified 21 gunshot wounds to the chest, left shoulder, arms and legs, including ten buckshot wounds from the initial shotgun blast.
Carlos is believed to have planned his attacks on several European targets, including the bombing of the Radio Free Europe offices in Munich in February 1981, which was part of an eventually unsuccessful hunt for Ion Mihai Pacepa ordered and financed by the Romanian government.
At the consistory of 21 February 2001, Archbishop Bergoglio was created a cardinal by Pope John Paul II with the title of cardinal priest of San Roberto Bellarmino, a church served by Jesuits and named for one; he was formally installed in that church the following 14 October.
Liu Jianlun, Hong Kong's first patient, checked into the Metropole Hotel on February 21, with a room on the ninth floor, specifically room 911. Even though he was already feeling somewhat ill he visited with his family and travelled around Hong Kong.
On 21 February 2016, 106-year Washington D.C. resident and school volunteer Virginia McLaurin visited the White House as part of Black History Month. When asked by the president why she was there, McLaurin said, "A Black president. A Black wife. And I’m here to celebrate Black history. That's what I'm here for".
On 21 February 2018, Weah made his first official visit outside Africa, to France, meeting French President Emmanuel Macron. The meeting focused on improving the relationship between France and Liberia and also sought French help for a sports development project in Africa.The meeting was also attended by Didier Drogba, Kylian Mbappé and FIFA president Gianni Infantino.
On 21 February, the head of the Russian Federal Security Service (FSB) said that Russian forces had killed five Ukrainian "saboteurs" that crossed into Russian territory, capturing one Ukrainian serviceman and destroying two armoured vehicles.
On 21 February 2022, Russia officially recognized the two breakaway regions in eastern Ukraine, the Donetsk People's Republic and the Luhansk People's Republic, as independent states, and deployed troops to Donbas, in a move interpreted as Russia's effective withdrawal from the Minsk Protocol.