Although initially unsuccessful in the Fourth Syrian War against Egypt, which led to a defeat at the Battle of Raphia (217 BC), Antiochus would prove himself to be the greatest of the Seleucid rulers after Seleucus I himself.
The Battle of Lake Trasimene was fought when a Carthaginian force under Hannibal ambushed a Roman army commanded by Gaius Flaminius on 21 June 217 BC, during the Second Punic War.