With AMD's introduction of a 64-bit architecture backwards-compatible with x86, x86-64 (also called AMD64), in September 2003, followed by Intel's near fully compatible 64-bit extensions (first called IA-32e or EM64T, later renamed Intel 64), the 64-bit desktop era began. Both versions can run 32-bit legacy applications without any performance penalty as well as new 64-bit software.
On Sep 8, Singapore announced that a post-doctoral worker in a SARS research lab in the National University of Singapore had contracted the disease while working on another virus but recovered shortly thereafter.
The steady European interest in Kaká culminated in his signing with the European champions, Italian club A.C. Milan, in 2003 for a fee of reported €8.5 million, described in retrospect as "peanuts" by club owner Silvio Berlusconi. Within a month, he cracked the starting lineup, replacing Rui Costa in the attacking midfield playmaking position, behind strikers Jon Dahl Tomasson, Filippo Inzaghi and Andriy Shevchenko.
The fifth ministerial conference (2003) was held in Cancún, Mexico, aiming at forging agreement on the Doha round. An alliance of 22 southern states, the G20 developing nations (led by India, China, Brazil, ASEAN led by the Philippines), resisted demands from the North for agreements on the so-called "Singapore issues" and called for an end to agricultural subsidies within the EU and the US. The talks broke down without progress.