Mr. & Mrs. Smith

In 2005, Jolie returned to major box office success with the action-comedy Mr. & Mrs. Smith, in which she starred opposite Brad Pitt as a bored married couple who find out that they are both secret assassins. With box office takings of $478.2 million worldwide, Mr. & Mrs. Smith was the seventh-highest grossing picture of the year and remained Jolie's highest-grossing live-action film for the next decade.