American Civil War broke out

When the American Civil War broke out, the Blackwell sisters aided in nursing efforts. Blackwell sympathized heavily with the North due to her abolitionist roots, and even went so far as to say she would have left the country if the North had compromised on the subject of slavery. However, Blackwell did meet with some resistance on the part of the male-dominated United States Sanitary Commission (USSC) . The male physicians refused to help with the nurse education plan if it involved the Blackwells. In response to the USSC, Blackwell organized with the Woman's Central Relief Association (WCRA). The WCRA worked against the problem of uncoordinated benevolence, but ultimately was absorbed by the USSC. Still, the New York Infirmary managed to work with Dorothea Dix to train nurses for the Union effort.