Alexander Balas was overthrown by Demetrius II Nicator

Alexander Balas reigned until 145 BC when he was overthrown by Demetrius I's son, Demetrius II Nicator. Demetrius II proved unable to control the whole of the kingdom, however. While he ruled Babylonia and eastern Syria from Damascus, the remnants of Balas' supporters – first supporting Balas' son Antiochus VI, then the usurping general Diodotus Tryphon – held out in Antioch.